Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198065 | 0.76 | MAPT (0.61) | KDM4EMAPTHSD17B10HIF1ATXNRD1 | |
| SCHEMBL2605854 | 0.75 | KDM4E (0.52) | KDM4EMAPTHSD17B10HIF1AACLY | |
| SCHEMBL28595233 | 0.73 | MAPT (0.42) | KDM4EMAPTHSD17B10HIF1ATXNRD1 | |
| SCHEMBL29903995 | 0.73 | MAPT (0.48) | KDM4EMAPTHSD17B10HIF1AACLY | |
| SCHEMBL30599258 | 0.73 | KDM4E (0.48) | KDM4EMAPTHSD17B10HIF1AACLY | |
| SCHEMBL29004074 | 0.72 | MAPT (0.44) | KDM4EMAPTHSD17B10HIF1AACLY | |
| SCHEMBL30342075 | 0.72 | MAPT (0.44) | KDM4EMAPTHSD17B10HIF1AACLY | |
| SCHEMBL28664956 | 0.71 | MAPT (0.56) | KDM4EMAPTHSD17B10HIF1ATXNRD1 | |
| SCHEMBL29004068 | 0.71 | MAPT (0.51) | KDM4EMAPTHSD17B10HIF1AACLY | |
| SCHEMBL2602433 | 0.71 | MAPT (0.51) | KDM4EMAPTHSD17B10HIF1ATXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844042-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006076529-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2006-07-20 | — | — | WO | disclosed |