Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263450 | 0.87 | KDR (0.54) | KDRAURKA | |
| SCHEMBL4981627 | 0.87 | KDR (0.69) | KDRAURKA | |
| SCHEMBL4980432 | 0.87 | KDR (0.58) | KDRAURKA | |
| Hydrochloric Acid SCHEMBL5225920 | 0.86 | KDR (0.53) | KDRAURKA | |
| SCHEMBL4978362 | 0.86 | KDR (0.68) | KDRAURKA | |
| SCHEMBL4983410 | 0.86 | KDR (0.61) | KDRAURKA | |
| SCHEMBL5226716 | 0.84 | KDR (0.55) | KDRAURKA | |
| SCHEMBL4978763 | 0.84 | KDR (0.54) | KDRAURKA | |
| SCHEMBL4976764 | 0.84 | KDR (0.55) | KDRAURKA | |
| Trifluoroacetic Acid SCHEMBL4978400 | 0.83 | KDR (0.57) | KDRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |