Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5917815 | 0.83 | CHRNA7 (0.48) | SMYD3CHRNA7HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL5231652 | 0.82 | CHRNA7 (0.47) | SMYD3CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL843682 | 0.80 | HDAC6 (0.42) | HDAC6SMYD3MAOBCHRNA7HTR3E | |
| SCHEMBL843795 | 0.80 | HDAC6 (0.40) | HDAC6SMYD3MAOBCHRNA7HTR3E | |
| SCHEMBL5918031 | 0.80 | SMYD3 (0.36) | SMYD3CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL5290539 | 0.80 | SMYD3 (0.58) | HDAC6SMYD3MAOBS1PR1ABL1 | |
| SCHEMBL5917824 | 0.79 | CHRNA7 (0.60) | SMYD3CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL5228643 | 0.79 | CHRNA7 (0.52) | SMYD3CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL6636807 | 0.79 | CHRNA7 (0.60) | SMYD3CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL5917825 | 0.79 | ABL1 (0.39) | CHRNA7HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425286-B1 | SUBSTITUTED 7-AZA-[2.2.1]BICYCLOHEPTANES FOR THE TREATMENT OF DISEASES | PHARMACIA & UPJOHN CO LLC (US) | 2007-02-28 | — | — | EP | claimed |