Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 7/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 1/20 | 0.49 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.49 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5151175 | 0.99 | CHRM2 (0.49) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5155536 | 0.89 | BDKRB1 (0.59) | BDKRB1F2PLGPLAUF10 | |
| Hydrochloric Acid SCHEMBL5151160 | 0.88 | BDKRB1 (0.48) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5171190 | 0.86 | CHRM2 (0.53) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5151120 | 0.84 | CHRM2 (0.53) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5237661 | 0.84 | CHRM2 (0.56) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5235637 | 0.84 | CHRM2 (0.64) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| Hydrochloric Acid SCHEMBL5151708 | 0.83 | CHRM2 (0.65) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| Hydrochloric Acid SCHEMBL5150984 | 0.83 | CHRM2 (0.57) | BDKRB1CHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5151412 | 0.83 | BDKRB1 (0.58) | BDKRB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |