SCHEMBL5227618

SCHEMBL5227618

CCN(CCN(C)C)C(=O)[C@H](C)N1CC[C@H](N(CC(N)=O)S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL5225369 0.97 F10 (0.71) F10
SCHEMBL5228475 0.94 F10 (0.78) F10
SCHEMBL5223998 0.94 F10 (0.83) F10
SCHEMBL5223512 0.92 F10 (0.78) F10
SCHEMBL5224492 0.91 F10 (0.79) F10
SCHEMBL6415892 0.91 F10 (0.79) F10
SCHEMBL5227546 0.91 F10 (0.77) F10
SCHEMBL5222713 0.90 F10 (0.84) F10
SCHEMBL5223427 0.90 F10 (0.70) F10
SCHEMBL6362437 0.90 F10 (0.70) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444201-B1 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS GLAXO GROUP LTD (GB) 2007-09-12 EP claimed