Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260041 | 1.00 | CHRNA7 (0.36) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL5917943 | 0.99 | CHRNA7 (0.35) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5231801 | 0.88 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5229421 | 0.86 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5226820 | 0.86 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5229781 | 0.85 | CHRNA7 (0.35) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6382564 | 0.85 | CHRNA7 (0.35) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL5917851 | 0.84 | CHRNA7 (0.35) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5917860 | 0.83 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL842775 | 0.83 | CHRNA7 (0.36) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425286-B1 | SUBSTITUTED 7-AZA-[2.2.1]BICYCLOHEPTANES FOR THE TREATMENT OF DISEASES | PHARMACIA & UPJOHN CO LLC (US) | 2007-02-28 | — | — | EP | claimed |