Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 20/20 | 0.65 |
| ▸ | CDK2 | P24941 | 20/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 20/20 | 0.65 |
| ▸ | IKBKB | O14920 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227358 | 0.93 | CCNA2 (0.77) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5225882 | 0.88 | CCNA2 (0.74) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5227457 | 0.87 | CCNA2 (0.84) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5227895 | 0.85 | CCNA2 (0.82) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5230415 | 0.84 | CCNA2 (0.84) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5232534 | 0.84 | CCNA2 (0.83) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5231191 | 0.84 | CCNA2 (0.64) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5228244 | 0.82 | CCNA2 (0.85) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5234523 | 0.82 | CCNA2 (0.84) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5232011 | 0.80 | CCNA2 (0.72) | CCNA2CDK2CCNA1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478357-B1 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2007-01-31 | — | — | EP | claimed |