Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991824 | 0.92 | MCHR1 (0.36) | MCHR1HRH3CCR5 | |
| SCHEMBL2985142 | 0.82 | MCHR1 (0.37) | MCHR1HRH3 | |
| SCHEMBL5228571 | 0.81 | EGFR (0.39) | — | |
| SCHEMBL5231883 | 0.81 | MCHR1 (0.40) | MCHR1HRH3CCR5 | |
| SCHEMBL2991825 | 0.80 | MCHR1 (0.37) | MCHR1HRH3CCR5 | |
| SCHEMBL2988690 | 0.78 | MCHR1 (0.41) | MCHR1HRH3CCR5 | |
| SCHEMBL5231614 | 0.74 | EGFR (0.38) | HRH3 | |
| SCHEMBL5232127 | 0.73 | EGFR (0.38) | — | |
| SCHEMBL2994293 | 0.72 | EGFR (0.40) | — | |
| SCHEMBL5231280 | 0.71 | HRH3 (0.32) | MCHR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |