Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499186 | 1.00 | HRH3 (0.54) | HRH3ALDH1A1KDM4EHPGDDPP7 | |
| Hydrochloric Acid SCHEMBL5151486 | 0.99 | HRH3 (0.52) | HRH3ALDH1A1KDM4EHPGDDPP7 | |
| SCHEMBL5059867 | 0.84 | AKT1 (0.60) | DPP4 | |
| SCHEMBL23211354 | 0.84 | DPP7 (0.56) | HPGDDPP7HDAC8DPP8DPP4 | |
| SCHEMBL18492863 | 0.84 | DPP4 (0.62) | DPP7HDAC8DPP8DPP4 | |
| SCHEMBL23211353 | 0.84 | DPP7 (0.56) | HPGDDPP7HDAC8DPP8DPP4 | |
| SCHEMBL31754288 | 0.83 | SLC7A5 (0.57) | HRH3ALDH1A1KDM4EHDAC8HDAC1 | |
| SCHEMBL8077871 | 0.83 | HDAC8 (0.68) | HPGDDPP7HDAC8DPP8DPP4 | |
| SCHEMBL1039399 | 0.83 | HDAC8 (0.68) | HPGDDPP7HDAC8DPP8DPP4 | |
| SCHEMBL14390395 | 0.83 | HDAC8 (0.67) | DPP7HDAC8DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |
| EP-1373233-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076964-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-10-03 | — | — | WO | disclosed |