Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 20/20 | 0.52 |
| ▸ | CDK2 | P24941 | 20/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 20/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227216 | 0.91 | CCNA2 (0.64) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5229486 | 0.89 | CCNA2 (0.57) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5229349 | 0.87 | CCNA2 (0.61) | CCNA2CDK2CCNA1 | |
| SCHEMBL5227818 | 0.81 | CCNA2 (0.71) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL6799888 | 0.78 | CCNA2 (0.80) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL6792687 | 0.77 | CCNA2 (0.65) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL5232538 | 0.77 | CCNA2 (0.66) | CCNA2CDK2CCNA1 | |
| Hydrochloric Acid SCHEMBL6794519 | 0.75 | CCNA2 (0.80) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL6793939 | 0.75 | CCNA2 (0.69) | CCNA2CDK2CCNA1IKBKB | |
| SCHEMBL6792712 | 0.75 | CCNA2 (0.65) | CCNA2CDK2CCNA1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478357-B1 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PFIZER ITALIA SRL (IT) | 2007-01-31 | — | — | EP | claimed |