Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.48 |
| ▸ | PPARD | Q03181 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229343 | 0.87 | PPARG (0.52) | PPARGPPARDPPARACYP2C9KCNH2 | |
| SCHEMBL5227996 | 0.87 | PPARG (0.49) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5230234 | 0.84 | PPARG (0.57) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5227897 | 0.84 | PPARG (0.56) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5224824 | 0.81 | PPARG (0.53) | PPARGPPARDPPARACYP2C9KCNH2 | |
| SCHEMBL5229702 | 0.81 | PPARG (0.51) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5227831 | 0.80 | PPARG (0.52) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5434773 | 0.80 | PPARG (0.47) | PPARGPPARDPPARACYP2C9KCNH2 | |
| SCHEMBL5227014 | 0.78 | PPARG (0.55) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL14361003 | 0.78 | PPARG (0.63) | PPARGPPARACYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |