SCHEMBL5229490

SCHEMBL5229490

CC(=O)ON(Cc1cccc(OCCc2coc(-c3ccccc3)n2)c1)[S+]([O-])N(C)C

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.50
PPARG P37231 16/20 0.46
FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5268317 0.86 PPARA (0.57) PPARAPPARG
SCHEMBL5229270 0.82 PPARA (0.51) PPARAPPARGFFAR1
SCHEMBL4389591 0.77 PPARA (0.55) PPARAPPARGFFAR1
SCHEMBL5229267 0.76 PPARA (0.58) PPARAPPARG
SCHEMBL5226562 0.76 FFAR1 (0.51) PPARAPPARGFFAR1
SCHEMBL4748568 0.76 KDR (0.53) PPARAPPARGFFAR1
SCHEMBL7156371 0.76 PPARA (0.50) PPARAPPARGFFAR1
SCHEMBL4391056 0.76 PPARA (0.56) PPARAPPARGFFAR1
SCHEMBL5230667 0.73 PPARA (0.50) PPARAPPARG
SCHEMBL4393196 0.73 PPARA (0.51) PPARAPPARGFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778654-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME Crystalgenomics, Inc. (KR) 2007-05-02 EP disclosed
WO-2006006832-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME CRYSTALGENOMICS, INC. (KR) 2006-01-19 WO disclosed