Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 20/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.62 |
| ▸ | HRH1 | P35367 | 5/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.62 |
| ▸ | HRH2 | P25021 | 4/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | HTR1B | P28222 | 1/20 | 0.62 |
| ▸ | HTR1E | P28566 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19521478 | 0.77 | TMEM97 (1.00) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL22022214 | 0.77 | PDK2 (0.53) | — | |
| SCHEMBL22291177 | 0.77 | TMEM97 (0.60) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL19521560 | 0.77 | TMEM97 (1.00) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL19521546 | 0.77 | TMEM97 (1.00) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL5237783 | 0.77 | TMEM97 (0.55) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL5229150 | 0.77 | TMEM97 (0.56) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL24091701 | 0.76 | TMEM97 (0.60) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL5232990 | 0.76 | TMEM97 (0.52) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL5237843 | 0.76 | KMT2A (0.54) | TMEM97SIGMAR1HRH1HRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |