Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 10/20 | 0.40 |
| ▸ | FLT3 | P36888 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940590 | 0.96 | MAPT (0.44) | MAPTL3MBTL1KITFLT3KMT2A | |
| SCHEMBL939996 | 0.89 | KIT (0.51) | MAPTL3MBTL1KITFLT3 | |
| SCHEMBL939862 | 0.89 | ADORA2A (0.47) | MAPTALDH1A1HPGDSMN1; SMN2ADORA3 | |
| SCHEMBL5964942 | 0.87 | MAPT (0.56) | MAPTL3MBTL1KITFLT3KMT2A | |
| SCHEMBL939892 | 0.87 | KIT (0.47) | MAPTL3MBTL1KITFLT3KMT2A | |
| SCHEMBL940762 | 0.87 | FLT3 (0.48) | MAPTL3MBTL1KITFLT3KMT2A | |
| SCHEMBL941784 | 0.86 | MAPT (0.43) | MAPTL3MBTL1KITFLT3KMT2A | |
| SCHEMBL1414488 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL940231 | 0.80 | ADORA2A (0.45) | MAPTALDH1A1HPGDSMN1; SMN2ADORA3 | |
| SCHEMBL2012739 | 0.79 | ADORA2A (0.47) | MAPTALDH1A1HPGDSMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663982-B1 | AMINOQUINOLINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | SANOFI AVENTIS (FR) | 2007-11-21 | — | — | EP | claimed |