Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 5/20 | 0.57 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5150928 | 0.99 | BDKRB1 (0.56) | BDKRB1BDKRB2PLGPLAUF10 | |
| SCHEMBL5231459 | 0.93 | BDKRB1 (0.60) | BDKRB1BDKRB2PLGPLAUF10 | |
| Hydrochloric Acid SCHEMBL5149020 | 0.92 | BDKRB1 (0.59) | BDKRB1BDKRB2PLGPLAUF10 | |
| SCHEMBL5232167 | 0.88 | BDKRB1 (0.56) | BDKRB1BDKRB2PLGPLAUF10 | |
| Hydrochloric Acid SCHEMBL5149072 | 0.87 | BDKRB1 (0.55) | BDKRB1BDKRB2PLGPLAUF10 | |
| SCHEMBL5171843 | 0.87 | BDKRB1 (0.62) | BDKRB1BDKRB2PLGPLAUF10 | |
| SCHEMBL5150917 | 0.87 | BDKRB1 (0.60) | BDKRB1BDKRB2PLGPLAUF10 | |
| Hydrochloric Acid SCHEMBL5150908 | 0.87 | BDKRB1 (0.58) | BDKRB1BDKRB2PLGPLAUF10 | |
| Hydrochloric Acid SCHEMBL5149069 | 0.86 | BDKRB1 (0.55) | BDKRB1BDKRB2PLGPLAUF10 | |
| SCHEMBL5155814 | 0.86 | BDKRB1 (0.63) | BDKRB1BDKRB2PLGPLAUF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |
| EP-1373233-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076964-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-10-03 | — | — | WO | disclosed |