Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5151181 | 0.94 | GRB2 (0.39) | OPRM1FAAHF2OPRK1PTPRC | |
| SCHEMBL5232357 | 0.76 | HPGD (0.38) | OPRM1FAAHF2ALOX5SLC7A5 | |
| SCHEMBL5232350 | 0.76 | F2 (0.36) | F2OPRK1SLC7A5 | |
| SCHEMBL5234301 | 0.74 | HDAC1 (0.48) | OPRM1FAAHF2ALOX5SLC7A5 | |
| SCHEMBL5154437 | 0.72 | HDAC8 (0.43) | F2SLC7A5 | |
| Trifluoroacetic Acid SCHEMBL5151176 | 0.72 | GRB2 (0.42) | OPRM1F2ALOX5OPRK1SLC7A5 | |
| Trifluoroacetic Acid SCHEMBL5151174 | 0.71 | GRB2 (0.40) | OPRM1F2OPRK1 | |
| Trifluoroacetic Acid SCHEMBL5150811 | 0.71 | GRB2 (0.44) | OPRM1F2ALOX5OPRK1SLC7A5 | |
| Trifluoroacetic Acid SCHEMBL5155526 | 0.69 | GRB2 (0.42) | OPRM1OPRK1SLC7A5 | |
| SCHEMBL5236489 | 0.68 | ACACB (0.49) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |
| EP-1373233-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076964-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-10-03 | — | — | WO | disclosed |