Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237415 | 0.86 | SMN1; SMN2 (0.52) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL5239237 | 0.85 | SMN1; SMN2 (0.53) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL31739572 | 0.83 | SMN1; SMN2 (0.51) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL30793617 | 0.81 | SMN1; SMN2 (0.53) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL5237806 | 0.81 | SMN1; SMN2 (0.51) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL1320424 | 0.80 | SMN1; SMN2 (0.58) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL3272711 | 0.80 | SMN1; SMN2 (0.58) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL3277927 | 0.80 | SMN1; SMN2 (0.58) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL7301326 | 0.80 | HTT (0.48) | SMN1; SMN2RAB9ANPC1CHRNB2CHRNA4 | |
| SCHEMBL13208750 | 0.80 | SMN1; SMN2 (0.54) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |