Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494430 | 0.93 | MEN1 (0.50) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4509473 | 0.86 | KMT2A (0.57) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4507747 | 0.85 | KMT2A (0.56) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL5236265 | 0.85 | KMT2A (0.56) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4496687 | 0.85 | KMT2A (0.56) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4510344 | 0.85 | KMT2A (0.56) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4506552 | 0.85 | KMT2A (0.56) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4517618 | 0.84 | KMT2A (0.55) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4506852 | 0.83 | KMT2A (0.57) | MEN1KMT2APGRSRCHDAC4 | |
| SCHEMBL4517818 | 0.83 | KMT2A (0.54) | MEN1KMT2APGRSRCHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776369-B1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | ACTIVE BIOTECH AB (SE) | 2007-10-10 | — | — | EP | disclosed |