Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 12/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271708 | 0.88 | EGLN1 (0.54) | VEGFAEGLN1ALDH1A1 | |
| SCHEMBL277620 | 0.85 | EGLN1 (0.71) | VEGFAEGLN1ALDH1A1MCHR1 | |
| SCHEMBL15255387 | 0.76 | EGLN1 (0.70) | VEGFAEGLN1 | |
| SCHEMBL12601411 | 0.73 | VEGFA (0.69) | VEGFAEGLN1ALDH1A1MCHR1OPRK1 | |
| SCHEMBL12650036 | 0.72 | VEGFA (0.50) | VEGFAEGLN1ALDH1A1OPRM1OPRK1 | |
| SCHEMBL272076 | 0.71 | VEGFA (0.85) | VEGFAEGLN1ALDH1A1 | |
| SCHEMBL272666 | 0.71 | VEGFA (0.81) | VEGFAEGLN1ALDH1A1 | |
| SCHEMBL272116 | 0.71 | VEGFA (0.85) | VEGFAEGLN1ALDH1A1 | |
| SCHEMBL278202 | 0.71 | VEGFA (1.00) | VEGFAEGLN1ALDH1A1 | |
| SCHEMBL12598863 | 0.71 | EGLN1 (0.63) | VEGFAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558579-B1 | N-ALKYL-4-METHYLENEAMINO-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIALS | PROCTER & GAMBLE (US) | 2007-09-12 | — | — | EP | claimed |