Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231112 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9ACYP2C19TMEM97 | |
| SCHEMBL5237427 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH | |
| SCHEMBL5233374 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9ACYP2C19SIGMAR1 | |
| SCHEMBL5232407 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH | |
| SCHEMBL27675705 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH | |
| SCHEMBL5235659 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH | |
| SCHEMBL20187093 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH | |
| SCHEMBL1841979 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH | |
| SCHEMBL27675706 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH | |
| SCHEMBL1841198 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ACYP2C19FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |