Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.61 |
| ▸ | CNR2 | P34972 | 16/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239434 | 0.93 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL5240619 | 0.90 | CNR1 (0.63) | CNR1CNR2KCNH2 | |
| SCHEMBL5236249 | 0.89 | CNR1 (0.75) | CNR1CNR2KCNH2 | |
| SCHEMBL5240695 | 0.88 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL5238605 | 0.86 | CNR1 (0.79) | CNR1CNR2KCNH2 | |
| SCHEMBL5238903 | 0.81 | CNR1 (0.70) | CNR1CNR2KCNH2 | |
| SCHEMBL5235768 | 0.81 | CNR1 (0.88) | CNR1CNR2 | |
| SCHEMBL5240735 | 0.80 | CNR1 (0.68) | CNR1CNR2KCNH2 | |
| SCHEMBL5235335 | 0.79 | CNR1 (0.68) | CNR1CNR2KCNH2 | |
| SCHEMBL20304636 | 0.79 | CNR1 (0.73) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558615-B1 | PURINE COMPOUNDS AND USE THEREOF AS CANNABINOID RECEPTOR LIGANDS | PFIZER PROD INC (US) | 2007-08-29 | — | — | EP | claimed |