Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570166 | 0.86 | KMT2A (0.35) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL2082309 | 0.86 | KMT2A (0.35) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL2082308 | 0.86 | KMT2A (0.35) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL5231750 | 0.84 | MEN1 (0.32) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL2082222 | 0.84 | PSEN1 (0.36) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL2082224 | 0.84 | PSEN1 (0.36) | MEN1MAPK1KMT2AGAABTK | |
| Oxalic Acid SCHEMBL2267135 | 0.83 | BTK (0.33) | MEN1MAPK1KMT2AGAABTK | |
| SCHEMBL4748874 | 0.79 | MEN1 (0.37) | MEN1MAPK1KMT2AGAADPP8 | |
| SCHEMBL2670376 | 0.79 | MEN1 (0.37) | MEN1MAPK1KMT2AGAADPP8 | |
| SCHEMBL25370190 | 0.78 | PSEN1 (0.34) | MEN1MAPK1KMT2AGAABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990654-B1 | SUBSTITUTED CYCLOBUTYLAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-6448266-B1 | COMPOUNDS SUCH AS 2-AMINO-7-(3-(3-AMINO-1-FLUOROCYCLOBUTAN-3-YL)PYRROLIDIN-1-YL)-6-FLUORO-1-(2-FLUORO-1-CYCLOPROPYL)-8-METHYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID; ANTIBACTERIAL ACTIVITY; STAPHYLOCOCCUS, PNEUMOCOCCUS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-0990654-A1 | SUBSTITUTED CYCLOBUTYLAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |