Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 19/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 18/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407594 | 0.84 | DPP4 (0.45) | DPP4DPP8DPP9 | |
| SCHEMBL1407597 | 0.84 | DPP4 (0.45) | DPP4DPP8DPP9 | |
| SCHEMBL1407693 | 0.70 | DPP4 (0.61) | DPP4DPP8DPP9 | |
| SCHEMBL1407696 | 0.70 | DPP4 (0.61) | DPP4DPP8DPP9 | |
| SCHEMBL1407605 | 0.69 | DPP4 (0.35) | DPP4DPP8DPP9 | |
| SCHEMBL1408154 | 0.69 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL1407964 | 0.68 | DPP4 (0.47) | DPP4DPP8DPP9 | |
| SCHEMBL1407840 | 0.68 | DPP4 (0.54) | DPP4DPP8DPP9 | |
| SCHEMBL13605115 | 0.66 | DPP4 (0.60) | DPP4DPP8DPP9 | |
| SCHEMBL8260399 | 0.66 | DPP4 (0.61) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836206-A1 | AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | Bristol-Myers Squibb Company (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071752-A1 | AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |