Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5151310 | 0.99 | DPP4 (0.47) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL5148914 | 0.84 | DPP4 (0.43) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL23211269 | 0.81 | DPP4 (0.57) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL15382612 | 0.81 | DPP4 (0.57) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL23211354 | 0.80 | DPP7 (0.56) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL23211353 | 0.80 | DPP7 (0.56) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL14390395 | 0.80 | HDAC8 (0.67) | DPP4HDAC8DPP7OPRD1 | |
| SCHEMBL23211484 | 0.79 | DPP4 (0.57) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL18492870 | 0.79 | DPP4 (0.64) | DPP4HDAC8DPP7DPP8FAP | |
| SCHEMBL3136106 | 0.79 | DPP4 (0.64) | DPP4HDAC8DPP7DPP8FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |
| EP-1373233-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076964-A1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-10-03 | — | — | WO | disclosed |