Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.56 |
| ▸ | FAP | Q12884 | 8/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.56 |
| ▸ | PREP | P48147 | 4/20 | 0.56 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15026074 | 0.81 | DPP4 (0.55) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL15024866 | 0.80 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL10982207 | 0.78 | ACE (0.62) | — | |
| SCHEMBL30729305 | 0.76 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL571628 | 0.76 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL30729255 | 0.76 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL28536705 | 0.76 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL1647354 | 0.76 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8212654 | 0.76 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL28609483 | 0.76 | DPP4 (0.68) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799683-A1 | HEXAHYDRO-PYRAZINO[1,2-A]PYRIMIDINE-4, 7-DIONE DERIVATIVES SUBSTITUTED WITH AMINO ACIDS | Sanofi-Aventis Deutschland GmbH (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006024390-A1 | HEXAHYDRO-PYRAZINO[1,2-A]PYRIMIDINE-4, 7-DIONE DERIVATIVES SUBSTITUTED WITH AMINO ACIDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-03-09 | — | — | WO | disclosed |