Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5239678

O=C(O)C(F)(F)F.O=C(O)c1ccno1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA4 P43681 2/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA7 P36544 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.38
GAA P10253 3/20 0.38
HDAC1 Q13547 1/20 0.37
GFER P55789 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
CPA1 P15085 1/20 0.35
RXFP2 Q8WXD0 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4752538 1.00 CHRNA4 (0.41) CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL112293 0.89
Hydrochloric Acid SCHEMBL6473638 0.87
SCHEMBL27835831 0.87
Water SCHEMBL27334970 0.87
Formic Acid SCHEMBL28287257 0.82 CHRNA4 (0.42) CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7
Trifluoroacetic Acid SCHEMBL17873964 0.77 KMT2A (0.56) KMT2AMEN1GAAHDAC1GFER
SCHEMBL27463002 0.76 PTPN1 (0.48) KMT2AMEN1GFERTDP1MAPT
SCHEMBL27520450 0.73 KMT2A (0.47) CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL27463003 0.73 KDM4C (0.39) CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106910-A1 DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR FLARE THERAPEUTICS INC. (US) 2025-05-22 WO disclosed
EP-1761542-A2 OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS F.HOFFMANN-LA ROCHE AG (CH) 2007-03-14 EP disclosed
WO-2005121145-A2 OCTAHYDRO-PYRROLO[3,4-C] DERIVATIVES AND THEIR USE AS ANTIVIRAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2005-12-22 WO disclosed