Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.57 |
| ▸ | CNR2 | P34972 | 9/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827955 | 0.97 | CNR1 (0.60) | CNR1CNR2ITGA4ITGB7 | |
| SCHEMBL4823270 | 0.94 | CNR1 (0.58) | CNR1CNR2ITGA4ITGB7 | |
| SCHEMBL14064694 | 0.90 | CNR1 (0.53) | CNR1CNR2ITGA4ITGB7 | |
| SCHEMBL4831230 | 0.90 | CNR1 (0.53) | CNR1CNR2ITGA4ITGB7 | |
| SCHEMBL4830008 | 0.87 | CNR1 (0.57) | CNR1CNR2 | |
| Trifluoroacetic Acid SCHEMBL4831441 | 0.86 | CNR1 (0.53) | CNR1CNR2ITGA4ITGB7 | |
| SCHEMBL14064712 | 0.83 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL4829829 | 0.83 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL4831420 | 0.83 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL4825699 | 0.83 | CNR1 (0.61) | CNR1CNR2ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490043-A4 | SPIROCYCLIC AMIDES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO INC (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1490043-A2 | SPIROCYCLIC AMIDES AS CANNABINOID RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082190-A2 | SPIROCYCLIC AMIDES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | disclosed |