Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239960 | 0.88 | GRM5 (0.34) | GRM5 | |
| SCHEMBL5244652 | 0.87 | FLT1 (0.34) | — | |
| SCHEMBL5210534 | 0.86 | GRM5 (0.35) | GRM5 | |
| SCHEMBL5645734 | 0.79 | AR (0.39) | — | |
| SCHEMBL5244481 | 0.78 | CYP1A2 (0.33) | — | |
| SCHEMBL5639883 | 0.78 | GRM5 (0.30) | GRM5 | |
| SCHEMBL5243348 | 0.78 | CNR1 (0.33) | GRM5 | |
| SCHEMBL5244059 | 0.77 | POLB (0.32) | — | |
| SCHEMBL5244657 | 0.77 | FLT1 (0.37) | — | |
| SCHEMBL5208166 | 0.75 | FLT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401826-B1 | PYRAZOLE DERIVATIVES AS HIV REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | claimed |