Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067863 | 0.89 | BTK (0.61) | BTK | |
| SCHEMBL1069347 | 0.89 | BTK (0.61) | BTK | |
| SCHEMBL1065246 | 0.87 | BTK (0.61) | BTK | |
| SCHEMBL1069418 | 0.86 | BTK (0.61) | BTK | |
| SCHEMBL1065248 | 0.84 | BTK (0.56) | BTK | |
| SCHEMBL12671997 | 0.84 | BTK (0.59) | BTK | |
| SCHEMBL1067646 | 0.83 | BTK (0.58) | BTK | |
| SCHEMBL16716411 | 0.83 | BTK (0.58) | BTK | |
| SCHEMBL1067644 | 0.81 | BTK (0.56) | BTK | |
| SCHEMBL1065919 | 0.81 | BTK (0.72) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863766-A2 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI Pharmaceuticals, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099075-A2 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI PHARMACEUTICALS, INC. (US) | 2006-09-21 | — | — | WO | disclosed |