Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155702 | 0.84 | TSHR (0.56) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL14763820 | 0.84 | TSHR (0.56) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL9841232 | 0.83 | TSHR (0.50) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL10911338 | 0.83 | TSHR (0.50) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL9841231 | 0.83 | TSHR (0.50) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL31193586 | 0.81 | TSHR (0.44) | TSHRTDP1L3MBTL1CA1CA2 | |
| SCHEMBL4781157 | 0.81 | TSHR (0.52) | TSHRTDP1L3MBTL1CYP2C19CA1 | |
| SCHEMBL2873754 | 0.81 | TSHR (0.52) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL20582042 | 0.81 | TSHR (0.52) | TSHRTDP1L3MBTL1CYP2C19CA1 | |
| SCHEMBL14193191 | 0.81 | TSHR (0.52) | TSHRTDP1L3MBTL1CYP2C19TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189505-A | Tricyclic gyrase inhibitors as antibacterial agents | TRIUS THERAPEUTICS INC | 2015-12-23 | — | — | CN | disclosed |
| CN-1968954-A | Thienopyridine Derivatives | SANKYO CO (JP) | 2007-05-23 | — | — | CN | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |