Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.72 |
| ▸ | CDK8 | P49336 | 1/20 | 0.72 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.61 |
| ▸ | CDK9 | P50750 | 14/20 | 0.61 |
| ▸ | CDK2 | P24941 | 4/20 | 0.60 |
| ▸ | CSF1R | P07333 | 3/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | CDK7 | P50613 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | LDHB | P07195 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242413 | 1.00 | CCNC (0.72) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL12056868 | 0.92 | CCNC (0.61) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL5203867 | 0.92 | CCNC (0.60) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL12698727 | 0.92 | CCNC (0.60) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL24411077 | 0.90 | CCNC (0.58) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL12056826 | 0.90 | CCNC (0.58) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL18286645 | 0.90 | CCNC (0.58) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL12056766 | 0.90 | CCNC (0.58) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL12056843 | 0.90 | CCNC (0.58) | CCNCCDK8CCNT1CDK9CDK2 | |
| SCHEMBL12056771 | 0.89 | CCNC (0.57) | CCNCCDK8CCNT1CDK9CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513821-B1 | PROTEIN KINASE INHIBITORS | CYTOPIA PTY LTD (AU) | 2007-10-31 | — | — | EP | disclosed |