SCHEMBL524308

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30436667	1.00	AR (0.50)	ARCYP46A1PGRMAPK1NR1I2
	SCHEMBL524307	1.00	AR (0.50)	ARCYP46A1PGRMAPK1NR1I2
	SCHEMBL1703087	0.92	AR (0.47)	ARCYP46A1PGRMAPK1NR1I2
	SCHEMBL1703090	0.92	AR (0.47)	ARCYP46A1PGRMAPK1NR1I2
	SCHEMBL9941766	0.86	AR (0.52)	ARCYP46A1PGRMAPK1NR1I2
	SCHEMBL9941767	0.86	AR (0.52)	ARCYP46A1PGRMAPK1NR1I2
	SCHEMBL28442385	0.86	AR (0.37)	ARCYP46A1PGRSMN1; SMN2CYP3A4
	SCHEMBL28441826	0.86	AR (0.37)	ARCYP46A1PGRSMN1; SMN2CYP3A4
	SCHEMBL1702851	0.85	AR (0.45)	ARSMN1; SMN2ALDH1A1
	SCHEMBL1702847	0.85	AR (0.45)	ARSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.