SCHEMBL5243129

SCHEMBL5243129

C1CCNNC1.CCNC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
HTT P42858 1/20 0.35
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
EPHX1 P07099 1/20 0.34
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MCL1 Q07820 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.31
FAAH O00519 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL28986107 0.83 EPHX1 (0.45) KMT2AHTTCYP2D6CYP2C19EPHX1
Piperazine SCHEMBL29116800 0.81 KMT2A (0.44) KMT2AHTTCYP2D6CYP2C19EPHX1
SCHEMBL10011 0.80
Bromide SCHEMBL1729291 0.77
Phosphine SCHEMBL28376179 0.77
Hydrochloric Acid SCHEMBL27431624 0.77
Propane SCHEMBL28986125 0.77
Hydrochloric Acid SCHEMBL29551256 0.77 CYP2D6 (0.46) KMT2AHTTCYP2D6CYP2C19MMP1
Water SCHEMBL28848094 0.77 MCL1 (0.46) KMT2AHTTCYP2D6CYP2C19MMP1
SCHEMBL29275148 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791816-A1 IODINE-PHENYL-SUBSTITUTED CYCLIC CETOENOLS Bayer CropScience Aktiengesellschaft (DE) 2007-06-06 EP disclosed
WO-2006029799-A1 IODINE-PHENYL-SUBSTITUTED CYCLIC CETOENOLS BAYER CROPSCIENCE AG (DE) 2006-03-23 WO disclosed