Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813490 | 0.85 | HSD17B10 (1.00) | HSD17B10LCKFYNTPMTGPR35 | |
| SCHEMBL5243855 | 0.83 | TSHR (0.53) | HSD17B10TPMTKDM4EHPGDALDH1A1 | |
| SCHEMBL30745030 | 0.83 | HSD17B10 (0.51) | HSD17B10TPMTKDM4EHPGDALDH1A1 | |
| SCHEMBL7813116 | 0.83 | HSD17B10 (0.71) | HSD17B10LCKFYNTPMTGPR35 | |
| SCHEMBL5240714 | 0.83 | HSD17B10 (0.51) | HSD17B10TPMTKDM4EHPGDALDH1A1 | |
| SCHEMBL2970067 | 0.82 | HSD17B10 (0.70) | HSD17B10LCKFYNTPMTGPR35 | |
| SCHEMBL15989607 | 0.82 | LCK (0.52) | HSD17B10LCKFYNKDM4EHPGD | |
| SCHEMBL30810187 | 0.81 | HSD17B10 (0.69) | HSD17B10LCKFYNTPMTGPR35 | |
| SCHEMBL30810298 | 0.81 | HSD17B10 (0.69) | HSD17B10LCKFYNTPMTGPR35 | |
| SCHEMBL9279881 | 0.81 | HSD17B10 (0.69) | HSD17B10LCKFYNTPMTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850364-B | Indian apple derivative and composition thereof, preparation method and application | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-1993343-A | Tetracyclic compounds as estrogen ligands | WYETH CORP (US) | 2007-07-04 | — | — | CN | disclosed |
| EP-1761513-A1 | TETRACYCLIC COMPOUNDS AS ESTROGEN LIGANDS | Wyeth (US) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006007503-A1 | TETRACYCLIC COMPOUNDS AS ESTROGEN LIGANDS | WYETH (US) | 2006-01-19 | — | — | WO | disclosed |
| US-20060004087-A1 | Tetracyclic compounds as estrogen ligands | WYETH (US) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004087-A1 | Tetracyclic compounds as estrogen ligands | ESR1, ESRRA, ESR2 | HSD17B10 2108/4885LCK 2235/4885FYN 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.