Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 20/20 | 1.00 |
| ▸ | DRD3 | P35462 | 19/20 | 1.00 |
| ▸ | DRD2 | P14416 | 16/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378348 | 1.00 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| SCHEMBL11915420 | 1.00 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| SCHEMBL5241929 | 1.00 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| SCHEMBL5241934 | 1.00 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| SCHEMBL378033 | 1.00 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL397496 | 0.99 | KCNH2 (0.98) | KCNH2DRD3DRD2 | |
| SCHEMBL5245984 | 0.94 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| SCHEMBL5245761 | 0.94 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| SCHEMBL378384 | 0.94 | KCNH2 (1.00) | KCNH2DRD3DRD2 | |
| SCHEMBL11911778 | 0.94 | KCNH2 (1.00) | KCNH2DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745040-A1 | AZABICYCLO(3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2007-01-24 | — | — | EP | claimed |
| WO-2005080382-A1 | AZABICYCLO (3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2005-09-01 | — | — | WO | claimed |