SCHEMBL5244302

SCHEMBL5244302

Cn1nccc1-c1cc(N)ccc1OCCN1CCCCOC1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 20/20 0.52
HTR2C P28335 17/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1166182 0.90 HTR2A (0.60) HTR2AHTR2C
SCHEMBL1166543 0.89 HTR2A (0.62) HTR2AHTR2C
SCHEMBL1167071 0.89 HTR2A (0.64) HTR2AHTR2C
SCHEMBL1166912 0.88 HTR2A (0.60) HTR2AHTR2C
SCHEMBL1166030 0.86 HTR2A (0.61) HTR2AHTR2C
SCHEMBL5245872 0.82 HTR2A (0.54) HTR2AHTR2C
SCHEMBL1167102 0.82 HTR2A (0.53) HTR2AHTR2C
SCHEMBL5246819 0.82 HTR2A (0.67) HTR2AHTR2C
SCHEMBL14374260 0.82 HTR2A (0.59) HTR2AHTR2C
SCHEMBL1167445 0.81 HTR2A (0.62) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833799-A2 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT-2a SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2007-09-19 EP disclosed
WO-2006055734-A2 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2006-05-26 WO disclosed