Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133246 | 0.93 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL5244249 | 0.93 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL4037933 | 0.93 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL5252644 | 0.92 | PDE5A (0.85) | PDE5AKCNH2 | |
| SCHEMBL5248379 | 0.92 | PDE5A (0.85) | PDE5AKCNH2 | |
| SCHEMBL8241142 | 0.92 | PDE5A (0.73) | PDE5AKCNH2 | |
| SCHEMBL5247307 | 0.91 | PDE5A (0.80) | PDE5AKCNH2 | |
| SCHEMBL5244928 | 0.91 | PDE5A (0.80) | PDE5AKCNH2 | |
| SCHEMBL5245313 | 0.87 | PDE5A (0.89) | PDE5AKCNH2 | |
| SCHEMBL5243921 | 0.86 | PDE5A (0.81) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809632-A2 | PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES USEFUL AS PDE-5 INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006046135-A2 | PYRAZOLO[4,3-D] PYRIMIDINE DERIVATIVES USEFUL AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-05-04 | — | — | WO | disclosed |