Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246536 | 0.92 | CNR2 (0.50) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5248272 | 0.91 | CNR2 (0.49) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5243466 | 0.91 | CNR2 (0.57) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5212563 | 0.90 | CNR2 (0.64) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5248345 | 0.86 | CNR2 (0.48) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5247243 | 0.86 | CNR2 (0.57) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5213189 | 0.82 | CNR2 (0.60) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5213781 | 0.81 | CNR2 (0.60) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5212880 | 0.81 | CNR2 (0.69) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL5250291 | 0.79 | CNR2 (0.81) | CNR2CYP2C9CYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | claimed |