Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244544 | 0.90 | HTR2A (0.58) | HTR2AHTR2C | |
| SCHEMBL5244020 | 0.88 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL5245783 | 0.84 | HTR2A (0.73) | HTR2AHTR2C | |
| SCHEMBL1167157 | 0.82 | HTR2A (0.92) | HTR2AHTR2C | |
| SCHEMBL5063298 | 0.82 | HTR2A (0.75) | HTR2AHTR2C | |
| SCHEMBL29573311 | 0.82 | HTR2A (0.75) | HTR2AHTR2C | |
| SCHEMBL1165806 | 0.81 | HTR2A (0.85) | HTR2AHTR2C | |
| SCHEMBL5243451 | 0.81 | HTR2A (0.68) | HTR2AHTR2C | |
| SCHEMBL1166581 | 0.81 | HTR2A (0.89) | HTR2AHTR2C | |
| SCHEMBL1165337 | 0.81 | HTR2A (0.98) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833799-A2 | 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT-2a SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006055734-A2 | 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2006-05-26 | — | — | WO | disclosed |