SCHEMBL5247170

SCHEMBL5247170

[CH2]COCCNCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5246124 0.95 CYP2C19 (0.36)
SCHEMBL27078262 0.95 CYP2C19 (0.36)
SCHEMBL5596696 0.85
SCHEMBL27558446 0.83 CYP2C19 (0.50)
SCHEMBL6236876 0.83 CYP2C19 (0.47)
SCHEMBL5596629 0.82
SCHEMBL5932913 0.80 CYP2C19 (0.53)
SCHEMBL3797316 0.80 CYP2C19 (0.45)
SCHEMBL5244237 0.78 TSHR (0.46)
SCHEMBL26465383 0.78 CYP2C19 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006065842-A2 5,6,7,8-TETRAHYDROQUINOLINES AND RELATED COMPOUNDS AND USES THEREOF SYNTA PHARMACEUTICALS CORP. (US) 2006-06-22 WO claimed
EP-1379598-B1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AG (DE) 2007-09-12 EP disclosed
EP-1829876-A1 NITROGENEOUS TRICYCLIC COMPOUND Asahi Kasei Pharma Corporation (JP) 2007-09-05 EP disclosed
US-20060247266-A1 Nitrogen-containing tricyclic compounds ASAHI KASEI PHARMA CORPORATION (JP) 2006-11-02 US disclosed
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed
EP-1379598-A1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AKTIENGESELLSCHAFT (DE) 2004-01-14 EP disclosed
EP-1311526-A1 PROCESSES FOR THE PREPARATION OF OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. (US) 2003-05-21 EP disclosed
WO-2002086000-A1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
WO-2002014340-A1 PROCESSES FOR THE PREPARATION OF OLIGONUCLEOTIDES_______________ ISIS PHARMACEUTICALS, INC. (US) 2002-02-21 WO disclosed
EP-0859284-A1 Water-developable photosensitive composition and production process thereof Nippon Paint Co., Ltd. (JP) 1998-08-19 EP disclosed