Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251316 | 0.91 | CNR2 (0.59) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5214843 | 0.91 | CNR2 (0.69) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5251628 | 0.87 | CNR2 (0.62) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5249860 | 0.87 | CNR2 (0.68) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5251172 | 0.85 | CNR2 (0.62) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5254469 | 0.85 | CNR2 (0.54) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5251306 | 0.85 | CNR2 (0.64) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5248606 | 0.84 | CNR2 (0.68) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5249925 | 0.83 | CNR2 (0.60) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5249738 | 0.83 | CNR2 (0.81) | CNR2CYP2D6CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | claimed |