Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211247 | 0.91 | AR (0.54) | ARSRD5A2SRD5A1 | |
| SCHEMBL7080627 | 0.87 | SRD5A1 (0.65) | ARSRD5A2SRD5A1 | |
| SCHEMBL5214662 | 0.87 | SRD5A1 (0.65) | ARSRD5A2SRD5A1 | |
| SCHEMBL13465160 | 0.84 | AR (0.70) | ARSRD5A2 | |
| SCHEMBL4458131 | 0.84 | AR (0.70) | ARSRD5A2 | |
| SCHEMBL8410044 | 0.84 | AR (0.70) | ARSRD5A2 | |
| SCHEMBL4458128 | 0.84 | AR (0.70) | ARSRD5A2 | |
| SCHEMBL14493967 | 0.84 | AR (0.70) | ARSRD5A2 | |
| SCHEMBL7624008 | 0.84 | AR (0.70) | ARSRD5A2 | |
| SCHEMBL9022119 | 0.84 | SRD5A2 (0.56) | ARSRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420796-A4 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1420796-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Merck & Co., Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003011302-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO., INC. (US) | 2003-02-13 | — | — | WO | disclosed |