Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668635 | 0.95 | HRH3 (0.56) | HRH3MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL21615694 | 0.93 | HRH3 (0.60) | HRH3MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL10272647 | 0.91 | MRGPRX4 (0.64) | MRGPRX4LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL23483168 | 0.89 | HRH3 (0.56) | HRH3MRGPRX4SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL15546216 | 0.87 | MAPT (0.64) | HRH3KDM4EKMT2ARAB9AGAA | |
| SCHEMBL4332979 | 0.86 | FOXM1 (0.55) | HRH3MRGPRX4SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL22139428 | 0.85 | HRH3 (0.62) | HRH3MRGPRX4LMNACYP1A2PTGS1 | |
| SCHEMBL5555630 | 0.84 | FOXM1 (0.56) | HRH3MRGPRX4SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL23785448 | 0.84 | HRH3 (0.52) | HRH3MRGPRX4MAOBRAB9AFOXM1 | |
| SCHEMBL24066732 | 0.84 | HRH3 (0.57) | HRH3MRGPRX4FOXM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833806-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006064189-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
| EP-1507763-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | Bayer HealthCare AG (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003097607-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-11-27 | — | — | WO | disclosed |
| US-4480052-A | COLORLESS DYE, PHENOL DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| US-4471073-A | FATTY AMIDES, BISPHENOL COMPOUNDS, DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-11 | — | — | US | disclosed |