Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | GLS2 | Q9UI32 | 2/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245204 | 0.81 | PTPN1 (0.52) | PTPN1HPGDPPARANR1H4GLS | |
| SCHEMBL1249955 | 0.79 | TTR (0.58) | HPGDNR1H4MEN1KMT2ATTR | |
| SCHEMBL157197 | 0.79 | TTR (0.58) | HPGDNR1H4MEN1KMT2ATTR | |
| SCHEMBL159267 | 0.76 | PIM1 (0.55) | PTPN1HPGDMEN1KMT2ATTR | |
| SCHEMBL1249059 | 0.76 | PIM1 (0.55) | PTPN1HPGDMEN1KMT2ATTR | |
| SCHEMBL1248928 | 0.73 | GSK3B (0.64) | PTPN1HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL1248930 | 0.73 | GSK3B (0.64) | PTPN1HPGDALDH1A1KDM4EPOLB | |
| SCHEMBL12891790 | 0.71 | PIM1 (0.83) | PTPN1HPGDGLSGLS2MEN1 | |
| SCHEMBL1248780 | 0.71 | PIM1 (0.83) | PTPN1HPGDGLSGLS2MEN1 | |
| SCHEMBL1248782 | 0.71 | PIM1 (0.83) | PTPN1HPGDGLSGLS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |