Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 12/20 | 0.43 |
| ▸ | DRD3 | P35462 | 11/20 | 0.43 |
| ▸ | HTR2A | P28223 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.43 |
| ▸ | HTR1A | P08908 | 8/20 | 0.43 |
| ▸ | HTR7 | P34969 | 8/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503114 | 0.95 | PIK3CD (0.57) | PIK3CDPIK3CBALKDRD2DRD3 | |
| SCHEMBL4498587 | 0.91 | PIK3CD (0.57) | PIK3CDPIK3CBALKDRD2DRD3 | |
| SCHEMBL4506508 | 0.89 | PIK3CD (0.59) | PIK3CDPIK3CBALKDRD2DRD3 | |
| SCHEMBL4505982 | 0.86 | PIK3CD (0.62) | PIK3CDPIK3CBALKPOLB | |
| SCHEMBL16674768 | 0.84 | PIK3CD (0.64) | PIK3CDPIK3CBALK | |
| SCHEMBL4505188 | 0.83 | PIK3CD (0.63) | PIK3CDPIK3CBALK | |
| SCHEMBL4499425 | 0.83 | ALK (0.49) | PIK3CDPIK3CBALKDRD2DRD3 | |
| SCHEMBL15068911 | 0.83 | PIK3CD (0.58) | PIK3CDPIK3CBALK | |
| Hydrochloric Acid SCHEMBL15069133 | 0.82 | PIK3CD (0.62) | PIK3CDPIK3CBALK | |
| SCHEMBL15069039 | 0.81 | PIK3CD (0.59) | PIK3CDPIK3CBALKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483262-B1 | COUMARINES USEFUL AS BIOMARKERS | NOVARTIS AG (CH) | 2007-11-14 | — | — | EP | disclosed |