Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | PRLHR | P49683 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2518090 | 1.00 | UTS2R (0.40) | UTS2RCCR5GCGRRORCPRLHR | |
| SCHEMBL5250135 | 0.94 | TP53 (0.41) | LMNATP53SLC6A5CYP2D6CYP2C9 | |
| SCHEMBL2517186 | 0.94 | TP53 (0.41) | LMNATP53SLC6A5CYP2D6CYP2C9 | |
| SCHEMBL2516227 | 0.94 | TP53 (0.41) | LMNATP53SLC6A5CYP2D6CYP2C9 | |
| SCHEMBL5252394 | 0.94 | TP53 (0.41) | LMNATP53SLC6A5CYP2D6CYP2C9 | |
| SCHEMBL5255954 | 0.91 | GCGR (0.41) | GCGRLMNATP53SLC6A5CYP2D6 | |
| SCHEMBL2515824 | 0.91 | GCGR (0.41) | GCGRLMNATP53SLC6A5CYP2D6 | |
| SCHEMBL2519249 | 0.91 | UTS2R (0.39) | UTS2RCCR5GCGRRORCPRLHR | |
| SCHEMBL5250752 | 0.91 | UTS2R (0.39) | UTS2RCCR5GCGRRORCPRLHR | |
| SCHEMBL2516248 | 0.87 | TP53 (0.44) | LMNATP53SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748980-A1 | PYRROLIDINE DERIVATIVES AS CB1-RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 2007-02-07 | — | — | EP | claimed |
| WO-2005115977-A1 | PYRROLIDINE DERIVATIVES AS CB1-RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 2005-12-08 | — | — | WO | claimed |
| EP-1748980-A1 | PYRROLIDINE DERIVATIVES AS CB1-RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005115977-A1 | PYRROLIDINE DERIVATIVES AS CB1-RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 2005-12-08 | — | — | WO | disclosed |