Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 10/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 9/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250938 | 1.00 | PTGER4 (0.56) | PTGER4PTGER3PTGER2KCNH2POLB | |
| SCHEMBL4385984 | 0.96 | PTGER4 (0.49) | PTGER4PTGER3PTGER2KCNH2POLB | |
| SCHEMBL4376516 | 0.96 | PTGER4 (0.49) | PTGER4PTGER3PTGER2KCNH2POLB | |
| SCHEMBL4385981 | 0.96 | PTGER4 (0.49) | PTGER4PTGER3PTGER2KCNH2POLB | |
| SCHEMBL4376510 | 0.96 | PTGER4 (0.49) | PTGER4PTGER3PTGER2KCNH2POLB | |
| SCHEMBL4377089 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL4377087 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL4377090 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL4377952 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL5794715 | 0.92 | PTGER4 (0.70) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817033-A1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE | Allergan, Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058080-A1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE | ALLERGAN, INC. (US) | 2006-06-01 | — | — | WO | disclosed |