SCHEMBL525402

SCHEMBL525402

C=COC(=O)[C@H](C)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080309 1.00
Trifluoroacetic Acid SCHEMBL30091831 0.86 TSHR (0.33)
SCHEMBL28859298 0.81 SLC7A5 (0.42)
SCHEMBL28859296 0.81 SLC7A5 (0.42)
SCHEMBL14790127 0.81 TSHR (0.34)
SCHEMBL93534 0.79
SCHEMBL19105201 0.79 TSHR (0.39)
SCHEMBL4201386 0.77
SCHEMBL12211509 0.77
SCHEMBL2886770 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802664-A1 PROCESS FOR THE SYNTHESIS OF SOLUBLE, HIGH MOLECULAR WEIGHT POLYMERS Johnson and Johnson Vision Care, Inc. (US) 2007-07-04 EP claimed
WO-2006044910-A1 PROCESS FOR THE SYNTHESIS OF SOLUBLE, HIGH MOLECULAR WEIGHT POLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-27 WO claimed
WO-2003057687-A1 METHODS FOR PREPARING DOXORUBICIN DERIVATIVES ALBANY MOLECULAR RESEARCH, INC. (US) 2003-07-17 WO claimed
EP-4630454-A1 METHODS OF TREATMENT USING B-CELL MATURATION ANTIGEN ANTAGONISTS GlaxoSmithKline Intellectual Property Development Ltd (GB) 2025-10-15 EP disclosed
WO-2024121711-A1 METHODS OF TREATMENT USING B-CELL MATURATION ANTIGEN ANTAGONISTS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2024-06-13 WO disclosed
CN-116359311-B Dynamic lactic acid sensor film and preparation method thereof 重庆联芯致康生物科技有限公司 2024-05-28 CN disclosed
EP-4355724-A1 SYNTHESIS OF VINYLATED HYDROXY ESTERS WITH APPLICABILITY IN SIGNAL ENHANCED MAGNETIC RESONANCE IMAGING Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-04-24 EP disclosed
CN-117813280-A Synthesis of vinyl hydroxyl esters suitable for signal enhanced magnetic resonance imaging 马克斯·普朗克科学促进协会 2024-04-02 CN disclosed
CN-116359311-A Dynamic lactic acid sensor film and preparation method thereof 重庆联芯致康生物科技有限公司 2023-06-30 CN disclosed
WO-2022263620-A1 SYNTHESIS OF VINYLATED HYDROXY ESTERS WITH APPLICABILITY IN SIGNAL ENHANCED MAGNETIC RESONANCE IMAGING Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) 2022-12-22 WO disclosed
EP-3481876-A1 SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF Johnson & Johnson Vision Care Inc. (US) 2019-05-15 EP disclosed
WO-2008036607-A2 POLYOLEFIN CONTACT LENS MOLDS AND USES THEREOF COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2008-03-27 WO disclosed
WO-2008021822-A2 INTERFERENCE FITTING POLAR RESIN OPHTHALMIC LENS MOLDING DEVICES AND RELATED METHODS COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2008-02-21 WO disclosed
WO-2007056591-A1 METHODS FOR STERILIZING SILICONE HYDROGEL CONTACT LENSES COOPERVISION INC. (US) 2007-05-18 WO disclosed
WO-2007021579-A2 CONTACT LENSES AND METHODS FOR REDUCING CONJUNCTIVAL PRESSURE IN CONTACT LENS WEARERS COOPERVISION, INC. (US) 2007-02-22 WO disclosed
EP-1716436-A1 (METH) ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES AND POLYMERS MADE THEREFROM Johnson and Johnson Vision Care, Inc. (US) 2006-11-02 EP disclosed
CN-1744908-A Amino acid-derived propofol prodrugs, compositions and uses thereof XENOPORT INC (US) 2006-03-08 CN disclosed
WO-2005078482-A1 (METH)ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES AND POLYMERS MADE THEREFROM JOHNSON & JOHNSON VISION CARE, INC. (US) 2005-08-25 WO disclosed
CN-1642550-A Beta-sheet mimetics and composition and methods relating thereto MYRIAD PHARMACEUTICALS INC (US) 2005-07-20 CN disclosed
CN-1396909-A inhibitors of the ICE/ced-3 family of cysteine proteases IDUN PHARMACEUTICALS INC (US) 2003-02-12 CN disclosed