Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.58 |
| ▸ | ABL1 | P00519 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 1/20 | 0.57 |
| ▸ | ABL2 | P42684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255493 | 0.96 | SRC (0.58) | SRCABL1BCRABL2 | |
| SCHEMBL5257159 | 0.94 | SRC (0.59) | SRCABL1BCR | |
| SCHEMBL5254306 | 0.94 | SRC (0.58) | SRCABL1BCR | |
| SCHEMBL5256702 | 0.93 | SRC (0.58) | SRCABL1BCR | |
| SCHEMBL5252360 | 0.92 | SRC (0.50) | SRCABL1BCRABL2 | |
| SCHEMBL5259354 | 0.88 | SRC (0.64) | SRCABL1BCRABL2 | |
| SCHEMBL5256043 | 0.88 | SRC (0.60) | SRCABL1BCR | |
| SCHEMBL6186103 | 0.87 | SRC (0.70) | SRCABL1BCR | |
| SCHEMBL5259214 | 0.87 | SRC (0.56) | SRCABL1BCR | |
| SCHEMBL5251932 | 0.87 | SRC (0.68) | SRCABL1BCRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242382-B1 | TRICYCLIC PROTEIN KINASE INHIBITORS | WYETH CORP (US) | 2007-02-07 | — | — | EP | claimed |