Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 11/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258502 | 0.86 | KCNH2 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL5255393 | 0.86 | KCNH2 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL5258498 | 0.86 | KCNH2 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL14434168 | 0.84 | KCNH2 (0.52) | KCNH2SLC2A1KMT2A | |
| SCHEMBL5258710 | 0.81 | KCNH2 (0.45) | KCNH2SLC2A1PRMT5WDR77 | |
| SCHEMBL5775045 | 0.79 | KCNH2 (0.52) | KCNH2SLC2A1PRMT5WDR77 | |
| SCHEMBL5257022 | 0.79 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL5255571 | 0.79 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL5255719 | 0.78 | SLC2A1 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL5253700 | 0.78 | KCNH2 (0.49) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359908-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERIDINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2007-08-22 | — | — | EP | claimed |